Study finds depression associated with greater risk of cardiovascular disease

A new study co-led by Simon Fraser University health sciences professor Scott Lear provides further evidence of the link between depressive symptoms and an increased risk of heart disease and early death. The global study tracked 145,862 middle-aged participants from 21 countries and found a 20 per cent increase in cardiovascular events and death in […]

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Adult stem cell study shows fish oil may help with depression

A study published in Molecular Psychiatry shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication. Using stem cells from adults with a clinical diagnosis of depression, the University of Illinois at Chicago researchers who conducted the study also found that fish oil, when […]

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Countering the Negative Effects of a Common Antidepressant

A depression medication carries a small risk for pregnant women of adverse side effects on their children’s development. Now a Tufts team might have found a way to counter these effects in fruit flies By Gina E. Mantica Selective serotonin reuptake inhibitors, or SSRI’s, are popular drugs that treat depression by increasing the amount of […]

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New therapy more effective than CBT for depression

A new therapy developed at The University of Manchester is better at treating depression than Cognitive Behavioural Therapy – or CBT – seen as the gold standard by psychologists and health providers. The study, published in Scientific Reports, is the first full-scale randomised trial of Metacognitive Therapy (MCT)- developed by Professor Adrian wells at Manchester, compared with […]

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Natural mood regulation low or even absent in people with depression

Periods of lockdown during the COVID-19 situation likely to exacerbate problems with mood regulation, say experts at the University of Oxford. Mood varies from hour-to-hour, day-to-day and healthy mood regulation involves choosing activities that help settle one’s mood. However, in situations where personal choices of activities are constrained, such as during periods of social isolation […]

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A biological mechanism for depression

University of Illinois at Chicago researchers report that in depressed individuals there are increased amounts of an unmodified structural protein, called tubulin, in lipid rafts — fatty sections of a cell membrane — compared with non-depressed individuals. Their findings are published in the Journal of Neuroscience. Tubulin is part of a protein complex that provides structure to […]

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Promising advance in depression research

Depression is a common psychiatric disorder and one of the leading causes of disability worldwide. Antidepressants are the first-line treatment for moderate to severe major depressive episodes. Despite their effectiveness, only 40% of patients respond to the first antidepressant they try. A recent paper in Nature Communication strongly suggests that a particular protein, GPR56, is involved in […]

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Could depression be linked to our cells’ metabolism?

EPFL researchers have discovered a compound that stimulates brain-cell metabolism and reduces signs of depression in mice. The next step will be to test their findings on humans. Chronic stress can be a major cause of depression. The exact mechanism of how that works isn’t clear, but the missing link could be found in the […]

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Surrey lithium monitor could improve lives of people suffering from bipolar

A wearable lithium drug monitor developed by the University of Surrey could change the lives of patients who suffer from bipolar and depression. It is estimated that bipolar disorder affects one in 100 people and lithium remains the most effective long-term therapy for the condition. It is incredibly important to monitor lithium intake as it […]

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